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KMID : 0371320110810020146
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Journal of the Korean Surgical Society
2011 Volume.81 No. 2 p.146 ~ p.150
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Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells
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Hur Young-Hoe
Kim Ho-Hyun
Seoung Ji-Shick
Koh Yang-Seok
Kim Jung-Chul
Kim Hyun-Jong
Cho Chol-Kyoon
Seo Kyoung-Won
Kim Jin-Woong
Jeong Yong-Yeon
Lee Jae-Hyuk
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Abstract
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Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of the exocrine pancreas. Some similar cases have been reported, but the histogenesis of these tumors varies and is controversial. We report here on a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells. A 77-year old woman presented with abdominal pain and anorexia. Abdominal computed tomography and magnetic resonance imaging showed an approximately 10 × 5 cm highly attenuated mass arising from the tail of the pancreas and invading the spleen and adjacent bowel loop. The initial impression was a malignant endocrine tumor or solid-pseudopapillary tumor of the pancreas. The patient underwent a distal pancreatectomy with splenectomy and left hemicolectomy. The histopathology and immunohistochemistry helped make the diagnosis that of an undifferentiated carcinoma with osteoclast-like giant cells of the pancreas.
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KEYWORD
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Osteoclast-like giant cells, Undifferentiated carcinoma, Pancreas
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